William DeFotis's compositions--instrumental, vocal, and electronic--have been performed throughout the United States and in Europe. His String Quartet was written for the LaSalle Quartet and his Continuous Showing was performed here and abroad by Percussion Group Cincinnati and later recorded by Opus One. Against That Time (10 songs on familiar texts for soprano, mezzo-soprano, and orchestra) was premiered by the University of Cincinnati College-Conservatory Philharmonia led by Gerhard Samuel his Openers (1999) was written for the Virginia Symphony Orchestra and its Music Director JoAnn Falletta. After his medical retirement from the College of William & Mary in 1996, he composed and recorded over a dozen satirical songs, included on Centaur Records' Satire is Serious Business CD. William DeFotis died of complications from chronic-progressive multiple sclerosis in 2003.